Glycolysis and Gluconeogenesis (Homo sapiens)

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Mitochondrion Cytosol 2P-Glycerate Pentose Phosphate Pathway Energy 1,3BP-Glycerate Acetyl-CoA 3P-Glycerate Fructose-1,6BP Glyceraldehyde 3P Pyruvate Fructose 6P Glucose Triglyceride synthesis Glycogen metabolism Dihydroxyacetone-P P-enolpyruvate Glucose-6P TCA Cycle PGK1 PGK2 HK1 HK3 HK2 GCK GAPDH GAPDHS ENO3 ENO1 ENO2 ALDOA ALDOC ALDOB LDHAL6B LDHA LDHC LDHB PFKP PFKM PFKL PGAM2 PGAM1 Glucose-6P (open) PGI Fructose 6P (open) Name: Glycolysis and Gluconeogenesis License: CC BY 2.0 Last Modified: 2/21/2013 Organism: Homo sapiens


Description

Glycolysis is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+. The free energy released in this process is used to form the ATP and NADH. Gluconeogenesis is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as pyruvate, lactate, glycerol, glucogenic amino acids, and fatty acids. Description adapted from Wikipedia.

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Ontology Terms

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Bibliography

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History

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RevisionActionTimeUserComment
97388view 21:42, 13 May 2018Khansperscleanup
97264view 20:45, 6 May 2018Ambar21pathway upload
96385view 16:57, 11 March 2018MarkAHershbergerModified title
94762view 08:51, 5 October 2017EgonwTagged interactions with mim-types.
93722view 07:48, 14 August 2017DeSlAdded nodes for open/closed forms of glucoses; changed IDs to (2-) forms where needed.
90450view 14:05, 16 November 2016KhanspersReverted to version '06:22, 10 September 2016' by Khanspers
90290view 15:57, 2 November 2016MirkoBaranziniSpecify description
90289view 15:55, 2 November 2016MirkoBaranziniPeriodical save, work in progress
90268view 23:39, 27 October 2016MirkoBaranziniSpecify description
90267view 23:37, 27 October 2016MirkoBaranziniSpecify description
90256view 01:48, 27 October 2016MirkoBaranziniPeriodical save, work in progress
90255view 01:36, 27 October 2016MirkoBaranziniPeriodical save, work in progress
90254view 01:26, 27 October 2016MirkoBaranziniPeriodical save, work in progress
90253view 01:15, 27 October 2016MirkoBaranziniPeriodical save, work in progress
90250view 15:22, 26 October 2016MirkoBaranziniSpecify description
90249view 14:53, 26 October 2016MirkoBaranzinisxq
90248view 14:49, 26 October 2016MirkoBaranziniSpecify description
90246view 13:35, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90245view 13:15, 26 October 2016MirkoBaranziniSpecify description
90239view 05:00, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90238view 04:56, 26 October 2016MirkoBaranziniGlicolisi1
90237view 04:54, 26 October 2016MirkoBaranziniSpecify description
90236view 04:50, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90235view 04:39, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90234view 04:36, 26 October 2016MirkoBaranziniSpecify description
90233view 04:17, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90232view 04:05, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90230view 03:56, 26 October 2016MirkoBaranziniGlicolisi 1
90229view 03:55, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90228view 03:50, 26 October 2016MirkoBaranziniSpecify description
90227view 03:45, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90226view 03:40, 26 October 2016MirkoBaranziniglico1
90223view 03:35, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90222view 03:25, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90221view 03:15, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90220view 03:05, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90219view 02:45, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90218view 02:34, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90217view 02:24, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90216view 02:14, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90215view 02:12, 26 October 2016MirkoBaranziniSpecify description
90214view 02:04, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90213view 02:03, 26 October 2016MirkoBaranziniglico 1
90212view 01:54, 26 October 2016MirkoBaranziniPeriodical save, work in progress
90211view 01:44, 26 October 2016MirkoBaranziniPeriodical save, work in progress
89372view 23:22, 9 September 2016EgonwConverted to interactions to graphical lines in the legend.
78585view 07:50, 7 January 2015MaintBotadded missing graphIds
74524view 14:59, 28 April 2014KhanspersModified description
74517view 10:08, 28 April 2014The HeraldModified description
72028view 05:56, 24 October 2013Mkutmonfixed unconnected lines

External references

DataNodes

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NameTypeDatabase referenceComment
1,3BP-GlycerateMetaboliteHMDB01270 (HMDB)
2P-GlycerateMetaboliteHMDB00362 (HMDB)
3P-GlycerateMetaboliteHMDB00807 (HMDB)
ALDOAGeneProduct226 (Entrez Gene)
ALDOBGeneProduct229 (Entrez Gene)
ALDOCGeneProduct230 (Entrez Gene)
Acetyl-CoAMetaboliteHMDB01206 (HMDB)
Dihydroxyacetone-PMetaboliteHMDB01473 (HMDB)
ENO1GeneProduct2023 (Entrez Gene)
ENO2GeneProduct2026 (Entrez Gene)
ENO3GeneProduct2027 (Entrez Gene)
EnergyMetabolite
Fructose 6P (open)MetaboliteCHEBI:57579 (ChEBI)fructose-6-phosphate (2-) open form
Fructose 6PMetabolite61527 (ChEBI)
Fructose-1,6BPMetaboliteHMDB01058 (HMDB)
GAPDHGeneProductENSG00000111640 (Ensembl)
GAPDHSGeneProduct26330 (Entrez Gene)
GCKGeneProduct2645 (Entrez Gene)Gck is mainly active in liver
Glucose-6P (open)MetaboliteCHEBI:57584 (ChEBI)D-Glucose-6-Phosphate (2-) open form
Glucose-6PMetaboliteCHEBI:75052 (ChEBI)Glucose-6-Phosphate (2-)
GlucoseMetaboliteHMDB00122 (HMDB)
Glyceraldehyde 3PMetaboliteHMDB01112 (HMDB)
Glycogen metabolismPathwayWP500 (WikiPathways)
HK1GeneProduct3098 (Entrez Gene)
HK2GeneProduct3099 (Entrez Gene)
HK3GeneProduct3101 (Entrez Gene)
LDHAGeneProduct3939 (Entrez Gene)
LDHAL6BGeneProduct92483 (Entrez Gene)
LDHBGeneProduct3945 (Entrez Gene)
LDHCGeneProduct3948 (Entrez Gene)
P-enolpyruvateMetaboliteHMDB00263 (HMDB)
PFKLGeneProduct5211 (Entrez Gene)
PFKMGeneProduct5213 (Entrez Gene)
PFKPGeneProduct5214 (Entrez Gene)
PGAM1GeneProduct5223 (Entrez Gene)
PGAM2GeneProduct5224 (Entrez Gene)
PGIGeneProduct5.3.1.9 (Enzyme Nomenclature)phosphoglucose isomerase (PGI)
PGK1GeneProduct5230 (Entrez Gene)
PGK2GeneProduct5232 (Entrez Gene)
Pentose Phosphate PathwayPathwayWP134 (WikiPathways)
PyruvateMetaboliteHMDB00243 (HMDB)
TCA CyclePathwayWP78 (WikiPathways)
Triglyceride synthesisPathwayWP325 (WikiPathways)

Annotated Interactions

<cite>No annotated interactions</cite>