Hypertrophy Model (Homo sapiens)

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protein synthesis angiogenesis Nucleus Extracellular -634 +500 correlate to all 4 MINOR probes proliferative response HB-EGF correlated +296 +1 -698 WDR1 EIF4EBP1 MINOR IL1R1 NR4A3 IL1A IFNG TCF8 GDF8 ADAM10 ANKRD1 ? MYOG IL18 VEGF CYR61 HBEGF IFRD1 EIF4E DUSP14 ATF3 JUND Name: Hypertrophy Model License: CC BY 2.0 Last Modified: 10/17/2013 Organism: Homo sapiens


Model of the effects of resistance exercise on gene regulation in human quadriceps muscle after an acute bout of isotonic exercise.

Quality Tags

Ontology Terms



  1. Zambon AC, McDearmon EL, Salomonis N, Vranizan KM, Johansen KL, Adey D, Takahashi JS, Schambelan M, Conklin BR; ''Time- and exercise-dependent gene regulation in human skeletal muscle.''; Genome Biol, 2003 PubMed


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97838view 23:54, 9 June 2018EgonwOntology Term : 'muscle cell' added !
97669view 01:05, 1 June 2018AMTanOntology Term : 'cardiac muscle cell' added !
94803view 16:50, 5 October 2017AlexanderPicoModified description
94802view 16:47, 5 October 2017AlexanderPicoConverted lines, compacted layout
88898view 00:57, 17 August 2016MirellaKalafatiOntology Term : 'disease pathway' added !
88647view 08:07, 12 August 2016JmeliusOntology Term : 'hypertrophic cardiomyopathy pathway' added !
71358view 11:35, 17 October 2013MaintBotAutomated update of data sources
62377view 18:09, 27 April 2013AlexanderPicoCleaned up groups and layout
45364view 13:54, 7 October 2011AlexanderPicoOntology Term : 'heart disease' added !
41035view 16:15, 1 March 2011MaintBotRemoved redundant pathway information and comments
38912view 13:49, 24 September 2010KhanspersChanged cellular compartments
38905view 13:40, 24 September 2010Khanspers
32131view 06:55, 14 August 2009MaintBotFixed group labels
21764view 04:32, 14 November 2008MaintBot[[Pathway:Homo sapiens:Hypertrophy model]] moved to [[Pathway:WP516]]: Moved to stable identifier
13983view 07:04, 20 May 2008Thomastransfered literature from comment
13981view 07:01, 20 May 2008Thomasconnected lines
10982view 07:00, 29 February 2008Derobcosmetic change
8146view 06:46, 7 January 2008MaintBot[[Pathway:Human:Hypertrophy model]] moved to [[Pathway:Homo sapiens:Hypertrophy model]]: Renaming species
7693view 09:10, 18 December 2007MaintBotfixed category names
7473view 05:42, 4 November 2007MaintBotAdded categories to GPML
6333view 15:17, 22 May 2007A.C.Zambongpml file for [[Human:Hypertrophy_model]]

External references


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NameTypeDatabase referenceComment
ADAM10GeneProduct102 (Entrez Gene)
ANKRD1GeneProduct27063 (Entrez Gene)
ATF3GeneProduct467 (Entrez Gene)
CYR61GeneProduct3491 (Entrez Gene)
DUSP14GeneProduct11072 (Entrez Gene)
EIF4EGeneProduct1977 (Entrez Gene)
EIF4EBP1GeneProduct1978 (Entrez Gene)
GDF8GeneProduct2660 (Entrez Gene)
HBEGFGeneProduct1839 (Entrez Gene)
IFNGGeneProduct3458 (Entrez Gene)
IFRD1GeneProduct3475 (Entrez Gene)
IL18GeneProduct3606 (Entrez Gene)
IL1AGeneProduct3552 (Entrez Gene)
IL1R1GeneProduct3554 (Entrez Gene)
JUNDGeneProduct3727 (Entrez Gene)
MYOGGeneProduct4656 (Entrez Gene)
NR4A3GeneProduct8013 (Entrez Gene)
TCF8GeneProduct6935 (Entrez Gene)
VEGFGeneProduct7422 (Entrez Gene)
WDR1GeneProduct9948 (Entrez Gene)

Annotated Interactions

<cite>No annotated interactions</cite>