Influenza A virus infection (Homo sapiens)

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Influenza A virus expression of late viral protein vRNP translocation (-) H+ Pathway: Viral Transcription and Replication (-) (-) mRNA export Nucleus (-) Pathway: Virus Assembly and Release vRNPs NP PB2 PB1 PA Influenza A virus matrix protein 1 PB1-F2 protein neuraminidase NS1 polymerase 1 PB2 NS2 nucleocapsid protein haemagglutinin matrix protein 2 PA haemagglutinin BCL2 Glutathione MIR34C N-Acetylneuraminic acid vRNPs Cytoplasm Endosome Influenza A virus Name: Influenza A virus infection Organism: Homo sapiens


The Influenza A virus infection pathway provides an overview of the key steps in the infection including virus assembly and release and viral transcription and replication.

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Ontology Terms



  1. Ji Q, Hao X, Meng Y, Zhang M, Desano J, Fan D, Xu L; ''Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres.''; BMC Cancer, 2008 PubMed


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96032view 08:41, 15 February 2018Mkutmonfix layout
96028view 08:39, 15 February 2018MkutmonModified description
94906view 16:40, 12 October 2017Khanspersconnected lines
94766view 09:06, 5 October 2017JmeliusConnect line
80038view 17:27, 1 May 2015KhanspersAdded MIR34C
78520view 03:29, 7 January 2015MaintBotadded missing graphIds
73327view 13:46, 20 January 2014MaintBotremoved erroneous biopax refs from gpml
73326view 13:44, 20 January 2014MaintBotremoved erroneous biopax refs from gpml
67953view 06:28, 28 June 2013DdiglesOntology Term : 'influenza A virus infection pathway' added !
63218view 14:01, 8 May 2013MaintBotUpdating gpml version
62378view 18:19, 27 April 2013AlexanderPicoCleaned up compartments and lines
45372view 14:03, 7 October 2011AlexanderPicoOntology Term : 'DOID:10528' removed !
45371view 14:03, 7 October 2011AlexanderPicoOntology Term : 'influenza' added !
44852view 02:51, 6 October 2011MartijnVanIerselOntology Term : 'HEMOPHILUS INFLUENZA INFECTION' added !
41038view 16:15, 1 March 2011MaintBotRemoved redundant pathway information and comments
33699view 04:30, 4 December 2009AndraModified categories
33698view 04:24, 4 December 2009AndraAdd content and reference from a paper discussing an effect to the Influenza A replication pathway
33697view 04:05, 4 December 2009AndraModified description
33376view 07:36, 30 November 2009MaintBotRemoved group label
33342view 09:55, 24 November 2009AndraNew pathway

External references


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NameTypeDatabase referenceComment
BCL2GeneProduct596 (Entrez Gene)
GlutathioneMetaboliteHMDB00125 (HMDB)
MIR34CRnaENSG00000207562 (Ensembl)
N-Acetylneuraminic acidMetaboliteHMDB00230 (HMDB)
NS1GeneProduct956533 (Entrez Gene)
NS2GeneProduct956532 (Entrez Gene)
PAGeneProduct956535 (Entrez Gene)
PB1-F2 proteinGeneProduct3802042 (Entrez Gene)
PB2GeneProduct956536 (Entrez Gene)
haemagglutinin GeneProduct956529 (Entrez Gene)
matrix protein 1GeneProduct956527 (Entrez Gene)
matrix protein 2GeneProduct956528 (Entrez Gene)
neuraminidaseGeneProduct956530 (Entrez Gene)
nucleocapsid proteinGeneProduct956531 (Entrez Gene)
polymerase 1GeneProduct956534 (Entrez Gene)

Annotated Interactions

<cite>No annotated interactions</cite>