This guide describes the recommended utilization of the most commonly used elements of the WikiPathways editor palette. Examples are taken directly from the WikiPathways archives. If you have questions about specific cases, contact the discussion mailing list.
For each figure, the original pathway is linked to from the image header.
Line / Arrow
The solid line and arrow are used to denote a variety of processes, including conversion, translocation, activation, binding and modification.
|Conversion||Receptor binding||Translocation between compartments||Activation by cAMP|
Dashed line / dashed arrow
The dashed line and arrow are used to denote an uncertain process or a process that involves additional steps not outlined in the diagram.
The T-bar is used to denote inhibition.
|Inhibition of enzymatic activity by a drug|
Any interaction can have a line style of either straight, curved, elbow or segmented. The default style is straight, and is shown in the examples above. The other three line styles are used to increase readability or to allow for a specific layout.
MIM Interactions - Molecular Interaction Maps
- GeneProduct: The default data node, used for proteins, RNA and genes.
- Metabolite: Used for any metabolite, drug or small molecule.
- Pathway: Used to denote a connection to another pathway.
- Protein: Used specifically for proteins.
- RNA: Used specifically for RNA, for example miRNA.
Graphical elements are purely graphical, meaning they do not have a meaning in the network graph that defines nodes and interactions.
Labels are used to describe locations, entities, processes or context:
|Labels used to indicate cell type||Labels used to indicate event||Labels used to describe complexes|
Lines can be used to create more complicated graphical objects representing biological structures, or to create a pathway legend.
|Multiple lines used to represent a sarcomere||Lines used to create a legend|
The arc is typically used to denote a cellular or molecular structure.
|Arcs used to represent a cellular structure|
The rectangle is typically used for headers, to create an outline for a legend or as a purely graphical object:
|Rectangle used as a header border|
Cellular compartment shapes are used to specify the cellular location of processes. Using the defined cellular compartment shapes instead of simple graphical shapes ensures that the cellular location information is encoded in the gpml.